Relationship of Serum Zinc Levels with Cardiometabolic Traits in Overweight and Obese Schoolchildren from Mexico City.

Zinc (Zn) participates as a cofactor for many enzymes in the cellular metabolism, and its serum levels have been associated with different metabolic diseases, especially obesity (OB). Nevertheless, its associations are not clear in the children population. The objective of this study is to evaluate the association between serum Zn levels (SZn) with overweight/obesity status (OW/OB), as well as its cardiometabolic traits in a population of children in Mexico City. Anthropometrical data (body mass index z score (BMIz)), demographic variables (age and sex), and cardiometabolic traits (total cholesterol (TC), high-density lipoprotein cholesterol (HDLc), low-density lipoprotein cholesterol (LDLc), triglycerides (TG), fasting plasma glucose (FPG), and insulin) were analyzed in this cross-sectional study. SZn were measured by inductively coupled plasma mass spectrometry (ICP-MS). The population included 210 children from Mexico City (girls (n = 105) and boys (n = 105)) between ages 6 and 10 years. Normal-weight (NW) schoolchildren had higher SZn concentrations (66 µg/dL; IQR: 48 to 91) compared to OW or OB schoolchildren (61 µg/dL; IQR: 45 to 76). The data showed a significant negative association between SZn and BMIz without sex exclusion (r = - 0.181 and p = 0.009). The boy's population did not show an association between the SZn and BMIz compared to the girl's population which showed a significant negative association (r = - 0.277 and p = 0.004). In addition, other associations were found between SZn and TC (boys (r = 0.214 and p = 0.025), LDLc (boys (r = 0.213 and p = 0.029), and TG (girls (r = - 0.260 and p = 0.007)). Moreover, 38.6% of the total children in our population study had Zn deficiency (ZnD). NW schoolchildren had higher SZn concentrations compared to OW or OB schoolchildren. A diet low in Zn can be a factor to evaluate in the development of childhood OB in Mexico. However, further studies need to be performed on the children Mexican population to replicate and confirm our findings.

[Distribution of triglycerides and glucose (TyG) index and homeostasis model assessment insulin resistance for the evaluation of insulin sensitivity on late adolescence in Mexicans]. / Distribución del índice triglicéridos y glucosa (TyG) y el modelo homeostático para la evaluación de la resistencia a la insulina en la adolescencia tardía en mexicanos.

Introduction: Introduction: when peripheral tissues don't respond well to insulin action, it is defined as insulin resistance (IR). Many methods and indices are available for the estimation of IR, among them the homeostasis model assessment of insulin resistance (HOMA-IR) involves fasting plasma glucose and insulin. Nevertheless, the TyG index has a methodological advantage over the HOMA-IR because it requires only measurements provided by routine laboratory tests. Aim: distribution asessment of the HOMA-IR and TyG indexes in the sample. Also, to determine the predictive capacity of HOMA-IR, using TyG cutoff point as IR-positive diagnostic test. Materials and methods: a cross-sectional analytical study with 1686 participants aged 18 to 21 years from the state of San Luis Potosí, Mexico. Anthropometric assessment involves variables of weight and height. Fasting glucose, insulin and triglyceride concentrations were quantified. In addition, a questionnaire was carried out to know the hereditary family history and the presence of noncommunicable diseases (NCDs). Student's t-test was used to assess the differences in mean statistics between males and females. A receiver operating characteristic (ROC) curve was applied to examine the potential of HOMA-IR to identify IR. Results: 56 % of the study adolescents were females and 44 % were males; mean BMI was 22.62 ± 3.21 kg/m2. In the total sample mean serum glucose, insulin, and triglyceride concentrations were 89.48 ± 9.84 mg/dL, 6.26 ± 5.04 µU/mL, and 95.64 ± 55.78 mg/dL, respectively. A prevalence of 28.2 % of IR was determined, evaluated with the cut-off points for the TyG index. Subsequently, Receiver Operator Curves (ROC) were performed to evaluate the predictive capacity of HOMA-IR. The most outstanding cut-off value was 1.08 for the HOMA-IR index, reaching a sensitivity of 66 % and a specificity of 53 %. The prevalence of HOMA-IR greater than or equal to 1.18 was 47 % in the total population, 19.3 % in males and 28.5 % in females Conclusions: HOMA-IR and TyG can be useful diagnostic parameters for the assessment of IR in late adolescence. To provide a health guide for IR, we propose that a HOMA-IR target value ≤ 1.08 should be considered.

Introducción: Introducción: cuando los tejidos periféricos tienen una incapacidad para responder a la acción de la insulina se denomina resistencia a la insulina (RI). Existen diferentes métodos para la identificación de la RI; uno de estos es el índice HOMA-IR, que utiliza los parámetros de laboratorio, glucosa e insulina en ayunas. El índice triglicéridos y glucosa (TyG) presenta la ventaja de solo necesitar análisis de laboratorio de rutina. Objetivo: evaluación de la distribución de los índices HOMA-IR y TyG en la población, así como determinar la capacidad predictiva del índice HOMA-IR utilizando el TyG como prueba diagnóstica para la RI. Materiales y métodos: estudio analítico transversal con 1686 participantes de 18 a 21 años del estado de San Luis Potosí. Se tomaron variables antropométricas de peso y talla y se cuantificó la concentración de glucosa, insulina y triglicéridos en ayuno. Además, se realizó un cuestionario para conocer los antecedentes heredofamiliares y la presencia de enfermedades no transmisibles (ENT). Para la comparación entre mujeres y hombres se realizó una prueba de la t de Student y se realizaron curvas operador receptor (COR) para determinar los valores de corte del HOMA-IR. Resultados: el 56 % de la población fueron mujeres y el 44 % hombres; la media del IMC fue de 22,62 ± 3,21 kg/m2. En la población total de estudio, la media de la concentración sérica de glucosa, insulina y triglicéridos fue de 89,48 ± 9,84 mg/dL, 6,26 ± 5,04 µU/mL y 95,64 ± 55,78 mg/dL, respectivamente. Se determinó una prevalencia del 28,2 % de la RI evaluada con los puntos de corte para el índice TyG. Posteriormente se realizaron curvas operador receptor (COR) para evaluar la capacidad predictiva del HOMA-IR. El valor de corte más destacado fue de 1,08 para el índice HOMA-IR, alcanzando una sensibilidad del 66 % y una especificidad del 53 %. La prevalencia del HOMA-IR mayor o igual a 1,18 fue del 47 % en la población total, del 19,3 % en los hombres y del 28,5 % en las mujeres. Conclusiones: los índices HOMA-IR y TyG pueden ser parámetros de utilidad diagnóstica para la valoración de la RI en la adolescencia tardía. Con el objetivo de brindar una guía de salud para la RI, proponemos que se debe considerar como objetivo un valor de HOMA-IR ≤ 1,08.

Distribución del índice triglicéridos y glucosa (TyG) y el modelo homeostático para la evaluación de la resistencia a la insulina en la adolescencia tardía en mexicanos / Distribution of triglycerides and glucose (TyG) index and homeostasis model assessment insulin resistance for the evaluation of insulin sensitivity on late adolescence in Mexicans

Introducción: cuando los tejidos periféricos tienen una incapacidad para responder a la acción de la insulina se denomina resistencia a la insulina (RI). Existen diferentes métodos para la identificación de la RI; uno de estos es el índice HOMA-IR, que utiliza los parámetros de laboratorio, glucosa e insulina en ayunas. El índice triglicéridos y glucosa (TyG) presenta la ventaja de solo necesitar análisis de laboratorio de rutina. Objetivo: evaluación de la distribución de los índices HOMA-IR y TyG en la población, así como determinar la capacidad predictiva del índice HOMA-IR utilizando el TyG como prueba diagnóstica para la RI. Materiales y métodos: estudio analítico transversal con 1686 participantes de 18 a 21 años del estado de San Luis Potosí. Se tomaron variables antropométricas de peso y talla y se cuantificó la concentración de glucosa, insulina y triglicéridos en ayuno. Además, se realizó un cuestionario para conocer los antecedentes heredofamiliares y la presencia de enfermedades no transmisibles (ENT). Para la comparación entre mujeres y hombres se realizó una prueba de la t de Student y se realizaron curvas operador receptor (COR) para determinar los valores de corte del HOMA-IR. (AU)

Introduction: when peripheral tissues don't respond well to insulin action, it is defined as insulin resistance (IR). Many methods and indices are available for the estimation of IR, among them the homeostasis model assessment of insulin resistance (HOMA-IR) involves fasting plasma glucose and insulin. Nevertheless, the TyG index has a methodological advantage over the HOMA-IR because it requires only measurements provided by routine laboratory tests. Aim: distribution asessment of the HOMA-IR and TyG indexes in the sample. Also, to determine the predictive capacity of HOMA-IR, using TyG cutoff point as IR-positive diagnostic test. Materials and methods: a cross-sectional analytical study with 1686 participants aged 18 to 21 years from the state of San Luis Potosí, Mexico. Anthropometric assessment involves variables of weight and height. Fasting glucose, insulin and triglyceride concentrations were quantified. In addition, a questionnaire was carried out to know the hereditary family history and the presence of noncommunicable diseases (NCDs). Student's t-test was used to assess the differences in mean statistics between males and females. A receiver operating characteristic (ROC) curve was applied to examine the potential of HOMA-IR to identify IR. (AU)

Prevalencia de la prediabetes y sus comorbilidades en la población pediátrica mexicana / Prevalence of prediabetes and its comorbidities in the Mexican pediatric population

Objetivo: la prediabetes es un estado que se observa antes de la diabetes de tipo 2. La actual epidemia de obesidad puede ser una causa del aumento de la incidencia de la prediabetes. En México existen políticas públicas para el manejo de las enfermedades no comunicables. Sin embargo, la obesidad continúa aumentando. Nuestro objetivo fue elaborar un diagnóstico de prediabetes en la población pediátrica mexicana y contrastar la proporción de comorbilidades que presentaban los niños con y sin prediabetes. Metodología: se realizó un estudio transversal analítico de 569 participantes de 4 a 19 años de edad procedentes de escuelas públicas. Se tomaron variables antropométricas (peso, talla y circunferencia de la cintura) y clínicas (presión arterial), así como indicadores bioquímicos (glucosa, perfil lipídico y ácido úrico). Resultados: el 8,6 % de la población presentaba prediabetes. Las variables de mayor prevalencia de alteración fueron los triglicéridos, seguidos de la presión arterial sistólica. Los hombres tenían prevalencias más altas de prediabetes, presión arterial elevada e hiperuricemia. Los niños con prediabetes tenían mayor riesgo de presentar cifras elevadas de circunferencia de la cintura, presión arterial y ácido úrico. Conclusiones: la población pediátrica mexicana tiene una prevalencia elevada de prediabetes. Además, se encontró que el grupo con prediabetes tiene mayor riesgo de presentar cifras elevadas de triglicéridos, presión arterial, ácido úrico y colesterol total. (AU)

Background: prediabetes is a state observed before type-2 diabetes. Nowadays the obesity epidemic could be due to a rise in the incidence of prediabetes. Mexico has public policies for the management of non-communicable diseases. However, obesity rates continue to increase. The aim of this study was to elaborate on a diagnosis of prediabetes in the pediatric Mexican population, and compare the proportions of comorbidities that children with and without prediabetes had. Methods: a cross-sectional study was performed with 569 participants of 4 to 19 years of age from public schools. Anthropometric (weight, height, and waist circumference), clinical (blood pressure), and biochemical (fasting glucose, lipidic profile, and uric acid) variables were collected. Results: in all, 8.6 % of the population had prediabetes. Variables with the highest altered prevalence included triglycerides and systolic blood pressure. Boys had higher rates of prediabetes, altered BP, and hyperuricemia than girls. Children with prediabetes had a greater risk of elevated waist circumference, blood pressure, and uric acid measures. Conclusions: the Mexican pediatric population had elevated rates of prediabetes. Furthermore, the group with prediabetes had a higher risk of presenting high values of triglycerides, blood pressure, uric acid, and total cholesterol. (AU)

Association between birthweight, cardiovascular risk factors, and depression in young Mexican adults / Asociación entre peso al nacer, riesgo cardiovascular y depresión en adultos jóvenes mexicanos

Background: the aim of this study was to investigate the association between birthweight, cardiovascular disease (CVD) risk factors, and depression in young Mexican adults. Methods: birthweight reports, family history of CVD and diabetes-related diseases, anthropometrics, serum lipid profile (total cholesterol [TC], triglycerides [TG], high-density lipoprotein-cholesterol [HDL-C], low-density lipoprotein-cholesterol [LDL-C], and very-low density lipoprotein-cholesterol [VLDL-C]), and depressive symptoms were measured in 778 subjects of the UP-AMIGOS cohort study. To investigate the association between birthweight categories and CVD risk factors and depression, a one-way analysis of variance with post-hoc test was performed of quantitative variables, and c2 test for qualitative variables. Results: mean age was 17.8 years and 469 (60.3 %) of patients were female (n = 469, 60.3 %). The percentage of patients with low birthweight (LBW) was 8.1 % (n = 63), and 3.3 % (n = 26) reported high birthweight (HBW). Young adults with HBW were associated with elevated diastolic blood pressure (DBP), and high weight and body mass index (BMI) when compared to LBW subjects, the difference being statically significant (p < 0.05). Birthweight had no significant association with depression (p > 0.67). Conclusion: the findings from this population-based study revealed a positive relation between birthweight categories and some CVD risk factors. Depression was not related to birthweight. (AU)

Introducción: el objetivo de este estudio fue investigar la asociación entre el peso al nacer, los factores de riesgo de las enfermedades cardiovasculares (ECV) y la depresión en adultos mexicanos jóvenes. Métodos: se obtuvieron como variables el peso al nacer, los antecedentes heredofamiliares de ECV y diabetes, la antropometría, el perfil lipídico (colesterol total [CT], triglicéridos [TG], lipoproteína de alta densidad [C-HDL], lipoproteína de baja densidad [C-LDL] y lipoproteína de muy baja densidad [C-VLDL]) y los síntomas de depresión de 778 participantes del estudio de cohortes UP-AMIGOS. Se realizó un análisis de la varianza de 1 vía con pruebas post hoc para investigar la asociación entre las categorías de peso al nacer, riesgo ECV y depresión entre las variables cuantitativas; para las variables cualitativas se realizaron pruebas del c2. Resultados: la edad media fue de 17,8 años y 469 (60,3 %) de los participantes eran mujeres. El porcentaje de pacientes con bajo peso al nacer (BPN) fue del 8,1 % (n = 63) y el 3,3 % (n = 26) tenían elevado peso al nacer (EPN). Se encontró una asociación en el grupo de EPN con la elevación de la presión arterial diastólica (PAS), el peso y el índice de masa corporal (IMC) al compararlo con el grupo de BPN, con una diferencia significativa de p < 0,05. No se encontró ninguna asociación entre el peso al nacer y la depresión (p > 0,67). Conclusiones: se encontró una relación positiva entre las categorías de peso al nacer con algunos factores de riesgo de ECV. La depresión no se asoció con el peso al nacer según los resultados de este estudio poblacional. (AU)

[Prevalence of prediabetes and its comorbidities in the Mexican pediatric population]. / Prevalencia de la prediabetes y sus comorbilidades en la población pediátrica mexicana.

INTRODUCTION: Background: prediabetes is a state observed before type-2 diabetes. Nowadays the obesity epidemic could be due to a rise in the incidence of prediabetes. Mexico has public policies for the management of non-communicable diseases. However, obesity rates continue to increase. The aim of this study was to elaborate on a diagnosis of prediabetes in the pediatric Mexican population, and compare the proportions of comorbidities that children with and without prediabetes had. Methods: a cross-sectional study was performed with 569 participants of 4 to 19 years of age from public schools. Anthropometric (weight, height, and waist circumference), clinical (blood pressure), and biochemical (fasting glucose, lipidic profile, and uric acid) variables were collected. Results: in all, 8.6 % of the population had prediabetes. Variables with the highest altered prevalence included triglycerides and systolic blood pressure. Boys had higher rates of prediabetes, altered BP, and hyperuricemia than girls. Children with prediabetes had a greater risk of elevated waist circumference, blood pressure, and uric acid measures. Conclusions: the Mexican pediatric population had elevated rates of prediabetes. Furthermore, the group with prediabetes had a higher risk of presenting high values of triglycerides, blood pressure, uric acid, and total cholesterol.

INTRODUCCIÓN: Objetivo: la prediabetes es un estado que se observa antes de la diabetes de tipo 2. La actual epidemia de obesidad puede ser una causa del aumento de la incidencia de la prediabetes. En México existen políticas públicas para el manejo de las enfermedades no comunicables. Sin embargo, la obesidad continúa aumentando. Nuestro objetivo fue elaborar un diagnóstico de prediabetes en la población pediátrica mexicana y contrastar la proporción de comorbilidades que presentaban los niños con y sin prediabetes. Metodología: se realizó un estudio transversal analítico de 569 participantes de 4 a 19 años de edad procedentes de escuelas públicas. Se tomaron variables antropométricas (peso, talla y circunferencia de la cintura) y clínicas (presión arterial), así como indicadores bioquímicos (glucosa, perfil lipídico y ácido úrico). Resultados: el 8,6 % de la población presentaba prediabetes. Las variables de mayor prevalencia de alteración fueron los triglicéridos, seguidos de la presión arterial sistólica. Los hombres tenían prevalencias más altas de prediabetes, presión arterial elevada e hiperuricemia. Los niños con prediabetes tenían mayor riesgo de presentar cifras elevadas de circunferencia de la cintura, presión arterial y ácido úrico. Conclusiones: la población pediátrica mexicana tiene una prevalencia elevada de prediabetes. Además, se encontró que el grupo con prediabetes tiene mayor riesgo de presentar cifras elevadas de triglicéridos, presión arterial, ácido úrico y colesterol total.

Association between birthweight, cardiovascular risk factors, and depression in young Mexican adults.

INTRODUCTION: Background: the aim of this study was to investigate the association between birthweight, cardiovascular disease (CVD) risk factors, and depression in young Mexican adults. Methods: birthweight reports, family history of CVD and diabetes-related diseases, anthropometrics, serum lipid profile (total cholesterol [TC], triglycerides [TG], high-density lipoprotein-cholesterol [HDL-C], low-density lipoprotein-cholesterol [LDL-C], and very-low density lipoprotein-cholesterol [VLDL-C]), and depressive symptoms were measured in 778 subjects of the UP-AMIGOS cohort study. To investigate the association between birthweight categories and CVD risk factors and depression, a one-way analysis of variance with post-hoc test was performed of quantitative variables, and 2 test for qualitative variables. Results: mean age was 17.8 years and 469 (60.3 %) of patients were female (n = 469, 60.3 %). The percentage of patients with low birthweight (LBW) was 8.1 % (n = 63), and 3.3 % (n = 26) reported high birthweight (HBW). Young adults with HBW were associated with elevated diastolic blood pressure (DBP), and high weight and body mass index (BMI) when compared to LBW subjects, the difference being statically significant (p < 0.05). Birthweight had no significant association with depression (p > 0.67). Conclusion: the findings from this population-based study revealed a positive relation between birthweight categories and some CVD risk factors. Depression was not related to birthweight.

INTRODUCCIÓN: Introducción: el objetivo de este estudio fue investigar la asociación entre el peso al nacer, los factores de riesgo de las enfermedades cardiovasculares (ECV) y la depresión en adultos mexicanos jóvenes. Métodos: se obtuvieron como variables el peso al nacer, los antecedentes heredofamiliares de ECV y diabetes, la antropometría, el perfil lipídico (colesterol total [CT], triglicéridos [TG], lipoproteína de alta densidad [C-HDL], lipoproteína de baja densidad [C-LDL] y lipoproteína de muy baja densidad [C-VLDL]) y los síntomas de depresión de 778 participantes del estudio de cohortes UP-AMIGOS. Se realizó un análisis de la varianza de 1 vía con pruebas post hoc para investigar la asociación entre las categorías de peso al nacer, riesgo ECV y depresión entre las variables cuantitativas; para las variables cualitativas se realizaron pruebas del 2. Resultados: la edad media fue de 17,8 años y 469 (60,3 %) de los participantes eran mujeres. El porcentaje de pacientes con bajo peso al nacer (BPN) fue del 8,1 % (n = 63) y el 3,3 % (n = 26) tenían elevado peso al nacer (EPN). Se encontró una asociación en el grupo de EPN con la elevación de la presión arterial diastólica (PAS), el peso y el índice de masa corporal (IMC) al compararlo con el grupo de BPN, con una diferencia significativa de p < 0,05. No se encontró ninguna asociación entre el peso al nacer y la depresión (p > 0,67). Conclusiones: se encontró una relación positiva entre las categorías de peso al nacer con algunos factores de riesgo de ECV. La depresión no se asoció con el peso al nacer según los resultados de este estudio poblacional.

The relationship between density of drug outlets, crime hot spots and family factors on the consumption of drugs and delinquent behaviour of male adolescent Mexican students.

This study examined the relationship between community risk factors (drug outlets density and crime hot spots) and family factors on the risk behaviours (drugs consumption and delinquent behaviour) of male adolescent Mexican students. Results were obtained based on data bank analysis and direct collection of information regarding family factors and risk behaviours of adolescents attending school. Spatial and statistical analysis was performed. The final sample was composed of 1450 male adolescents, from 11 secondary and high schools located in marginal and violent areas of Mexico. Spatial analysis revealed that when considering only the prevalence of the risk behaviours of the adolescents, the area of highest risk was the northwestern area of the city. However, after performing conjunct analysis of all evaluated variables using density point risk (aside from confirming that the northwestern area is still the one with the greatest risk), results indicated that the southern area has a high-density point risk. All densities of the variables showed a statistically significant positive association (p < 0.05). However, the results of the structural equation model indicated than only the family factors influenced the risk behaviours of adolescents (p < 0.05). The spatial distribution of the risk behaviours in male adolescent students and community risk variables surrounding the area where schools are located allows for the description of patterns and hotspot detection that facilitate the prioritization of where interventions must be directed. Besides, the interventions should target family factors.

Neck Circumference and Its Association with Cardiometabolic Risk Factors in Pediatric Population.

Background and objectives: To identify the relationship between neck circumference (NC) and cardiometabolic risk factors in children. Materials and Methods: Children and adolescents 6-18 years old (n = 548) from five counties of San Luis Potosí, México were included. Data was collected for biological markers (glucose and lipid profile) and anthropometric and clinical measurements-weight, height, NC, waist circumference (WC), and blood pressure (BP). Body mass index (BMI) was calculated using Quetelet formula (kg/m2). Descriptive analysis, correlation tests, and receiver operating characteristic (ROC) analysis were performed. Results: NC was highly correlated with BMI and WC in both genders (p <0.0001). The most frequent risk factor was high BMI (38.7%). Sensitivity and specificity analysis of NC and high BMI showed an area under the ROC curve of 0.887. Conclusions: According to our findings, NC is a simple, low-cost, and non-invasive measurement, which has a high association with high BMI and increased WC.

[Validity of a resilience scale (RESI-M) in indigenous women in Mexico]. / Validez de una escala de resiliencia (RESI-M) en mujeres indígenas de México.

Resilience encompasses a series of capacities and skills that individuals acquire through interaction with their context, thus succeeding in overcoming their own limits of resistance by generating more efficient defensive and protective mechanisms and processes than before when exposed to adverse events. Resilience is assessed by measuring the adverse situation, successful adaptation, and the process, which has led to the development of a variety of instruments. There is no instrument in the literature that contemplates resilience from the cultural perspective of indigenous women, so the aim of this study was to assess the validity and reliability of scores obtained with the scale in this population group. The sample included 180 participants from various indigenous communities in Mexico, who were submitted to the Mexican Resilience Scale (RESI-M) developed by Palomar Lever & Gómez Valdez 2010. Internal consistency was assessed with the Cronbach's alpha reliability coefficient, and the internal structure of each dimension was determined by principal components factor analysis with Varimax rotation. Mean age of participants was 33±9.4 years. Following analysis of the reliability and statistical validity, a final version of the instrument was obtained with 34 questions (from the original 43), with an acceptable reliability of 0.942 (Cronbach's alpha) and with 6 factors that explain 56.34% of total variance. The version is valid and reliable, with a structure that allows assessing resilience as a process in indigenous women.

La resiliencia engloba una serie de capacidades y habilidades, las cuales son adquiridas como resultado de la interacción del individuo con su contexto, logrando superar sus propios límites de resistencia, a través de la generación de mecanismos, procesos de defensa y protección más eficientes que antes, ante la exposición a eventos adversos. La medición de la resiliencia se hace a través de la medición de la adversidad, adaptación exitosa y el proceso, lo que ha generado en la actualidad una variedad de herramientas. En la literatura no existe un instrumento que contemple la resiliencia desde una perspectiva cultural indígena y en mujeres, por lo tanto, el objetivo de este estudio fue evaluar la validez y confiabilidad de las puntuaciones obtenidas con esta escala, al ser aplicada en mujeres indígenas. La muestra la integraron 180 participantes, pertenecientes a diversas localidades indígenas de México, a las cuales se les aplicó la Escala de Resiliencia Mexicana (RESI-M) de Palomar Lever & Gómez Valdez 2010. Se evaluó la consistencia interna mediante el coeficiente de fiabilidad alfa de Cronbach y se determinó la estructura interna de cada una de las dimensiones por medio de un análisis factorial de componentes principales con rotación Varimax. La edad media de las participantes fue de 33±9,4 años de edad. Tras los análisis de confiabilidad y validez estadística, se obtuvo una versión final del instrumento de 34 preguntas, de las 43 originales; con una confiabilidad aceptable de 0,942 (alfa de Cronbach) y con 6 factores que explican el 56,34% de la varianza total. La versión es válida y confiable, con una estructura que permite evaluar la resiliencia como un proceso en mujeres indígenas.

A resiliência inclui uma série de capacidades e habilidades, as quais são adquiridas como resultado da interação do individuo com seu contexto, conseguindo superar seus próprios limites de resistência, através da geração de mecanismos, processo de defesa e proteção mais eficientes do que antes, diante da exposição a eventos adversos. A medição da resiliência é feita por meio da medição da adversidade, adaptação exitosa e o processo, o que tem gerado na atualidade várias ferramentas. Na literatura não existe um instrumento que considere a resiliência desde uma perspectiva cultural indígena ao respeito das mulheres, portanto, este estudo teve como objetivo avaliar a validade e confiabilidade das pontuações obtidas com esta escala, a serem aplicadas em mulheres indígenas. A mostra foi integrada por 180 participantes, pertencentes a diversas municipalidades indígenas do México, onde foi aplicada a Escala de Resiliência Mexicana (RESI-M) de Palomar Lever & Gómez Valdez 2010. Foi avaliada a consistência interna por meio do coeficiente de confiabilidade alfa de Cronbach e foi determinada a estrutura interna de cada uma das dimensões por meio de uma análise fatorial de componentes principais com rotação Varimax. A idade media das participantes foi de 33±9,4 anos de idade. Depois das análises de confiabilidade e validade estatística, foi obtida uma versão final do instrumento com 34 perguntas, das 43 originais; com uma confiabilidade aceitável de 0,942 (alfa de Cronbach) e com 6 fatores que explicam o 56,34% da variância total. A versão é válida e confiável, com uma estrutura que permite avaliar a resiliência como um processo em mulheres indígenas.

Validez de una escala de resiliencia (RESI-M) en mujeres indígenas de México / Validity of a resilience scale (RESI-M) in indigenous women in Mexico / Validade de uma escala de resiliência (RESI-M) em mulheres indígenas do México

Resumen: La resiliencia engloba una serie de capacidades y habilidades, las cuales son adquiridas como resultado de la interacción del individuo con su contexto, logrando superar sus propios límites de resistencia, a través de la generación de mecanismos, procesos de defensa y protección más eficientes que antes, ante la exposición a eventos adversos. La medición de la resiliencia se hace a través de la medición de la adversidad, adaptación exitosa y el proceso, lo que ha generado en la actualidad una variedad de herramientas. En la literatura no existe un instrumento que contemple la resiliencia desde una perspectiva cultural indígena y en mujeres, por lo tanto, el objetivo de este estudio fue evaluar la validez y confiabilidad de las puntuaciones obtenidas con esta escala, al ser aplicada en mujeres indígenas. La muestra la integraron 180 participantes, pertenecientes a diversas localidades indígenas de México, a las cuales se les aplicó la Escala de Resiliencia Mexicana (RESI-M) de Palomar Lever & Gómez Valdez 2010. Se evaluó la consistencia interna mediante el coeficiente de fiabilidad alfa de Cronbach y se determinó la estructura interna de cada una de las dimensiones por medio de un análisis factorial de componentes principales con rotación Varimax. La edad media de las participantes fue de 33±9,4 años de edad. Tras los análisis de confiabilidad y validez estadística, se obtuvo una versión final del instrumento de 34 preguntas, de las 43 originales; con una confiabilidad aceptable de 0,942 (alfa de Cronbach) y con 6 factores que explican el 56,34% de la varianza total. La versión es válida y confiable, con una estructura que permite evaluar la resiliencia como un proceso en mujeres indígenas.

Abstract: Resilience encompasses a series of capacities and skills that individuals acquire through interaction with their context, thus succeeding in overcoming their own limits of resistance by generating more efficient defensive and protective mechanisms and processes than before when exposed to adverse events. Resilience is assessed by measuring the adverse situation, successful adaptation, and the process, which has led to the development of a variety of instruments. There is no instrument in the literature that contemplates resilience from the cultural perspective of indigenous women, so the aim of this study was to assess the validity and reliability of scores obtained with the scale in this population group. The sample included 180 participants from various indigenous communities in Mexico, who were submitted to the Mexican Resilience Scale (RESI-M) developed by Palomar Lever & Gómez Valdez 2010. Internal consistency was assessed with the Cronbach's alpha reliability coefficient, and the internal structure of each dimension was determined by principal components factor analysis with Varimax rotation. Mean age of participants was 33±9.4 years. Following analysis of the reliability and statistical validity, a final version of the instrument was obtained with 34 questions (from the original 43), with an acceptable reliability of 0.942 (Cronbach's alpha) and with 6 factors that explain 56.34% of total variance. The version is valid and reliable, with a structure that allows assessing resilience as a process in indigenous women.

Resumo: A resiliência inclui uma série de capacidades e habilidades, as quais são adquiridas como resultado da interação do individuo com seu contexto, conseguindo superar seus próprios limites de resistência, através da geração de mecanismos, processo de defesa e proteção mais eficientes do que antes, diante da exposição a eventos adversos. A medição da resiliência é feita por meio da medição da adversidade, adaptação exitosa e o processo, o que tem gerado na atualidade várias ferramentas. Na literatura não existe um instrumento que considere a resiliência desde uma perspectiva cultural indígena ao respeito das mulheres, portanto, este estudo teve como objetivo avaliar a validade e confiabilidade das pontuações obtidas com esta escala, a serem aplicadas em mulheres indígenas. A mostra foi integrada por 180 participantes, pertencentes a diversas municipalidades indígenas do México, onde foi aplicada a Escala de Resiliência Mexicana (RESI-M) de Palomar Lever & Gómez Valdez 2010. Foi avaliada a consistência interna por meio do coeficiente de confiabilidade alfa de Cronbach e foi determinada a estrutura interna de cada uma das dimensões por meio de uma análise fatorial de componentes principais com rotação Varimax. A idade media das participantes foi de 33±9,4 anos de idade. Depois das análises de confiabilidade e validade estatística, foi obtida uma versão final do instrumento com 34 perguntas, das 43 originais; com uma confiabilidade aceitável de 0,942 (alfa de Cronbach) e com 6 fatores que explicam o 56,34% da variância total. A versão é válida e confiável, com uma estrutura que permite avaliar a resiliência como um processo em mulheres indígenas.

Prevalencia mundial de la diabetes mellitus tipo 2 y su relación con el índice de desarrollo humano

Objetivo. Evaluar la relación entre la prevalencia de diabetes mellitus tipo 2 (DM2) y el índice de desarrollo humano (IDH) por región del mundo en el período 2010–2015. Método. Se utilizaron los datos de la Federación Internacional de Diabetes para la prevalencia de DM2 (2010–2015) y el IDH del Programa de las Naciones Unidas para el Desarrollo. Se analizaron correlaciones lineales de Spearman entre el IDH y la prevalencia de DM2 y se hicieron regresiones lineales para estimar la relación entre ambos. Resultados. Se observó que a menor IDH menores son las prevalencias de DM2, y a mayor IDH, mayores son las prevalencias de DM2. A nivel mundial, el IDH explica 8,6% de la varianza de la prevalencia de DM2 (P < 0,0001) y que este comportamiento fue diferente en cada región del mundo. Conclusiones. El IDH puede influir en la prevalencia de DM2, aunque la relación depende de cada país, región y año analizado.

Objective. To evaluate the relationship between the prevalence of type 2 diabetes mellitus (DM2) and the Human Development Index (HDI), by region of the world in the period 2010-2015. Method. International Diabetes Federation data were used for DM2 prevalence (2010-2015), together with HDI data (United Nations Development Program). Spearman linear correlations between HDI data and DM2 prevalence were analyzed, and linear regressions were done to estimate the relationship between the two. Results. It was observed that lower HDI scores corresponded to lower DM2 prevalence rates, and higher HDI scores to higher DM2 prevalence. At the global level, the HDI explains the 8.6% variance of DM2 prevalence (P < 0.0001) and shows that the situation was different in each region of the world. Conclusions. While HDI score may be associated with DM2 prevalence, the relationship between them differs from region to region and from country to country, and depends on the particular year analyzed.

Objetivo. Avaliar a relação entre a prevalência de diabetes mellitus tipo 2 (DM2) e o índice de desenvolvimento humano (IDH) por região do mundo no período de 2010 a 2015. Métodos. Foram utilizados dados da Federação Internacional de Diabetes para a prevalência da DM2 (2010–2015) e o IDH do Programa das Nações Unidas para o Desenvolvimento. Foram analisadas as correlações lineares de Spearman entre o IDH e a prevalência de DM2 e feitas regressões lineares para estimar a relação entre ambos. Resultados. Observou-se que quanto mais baixo o IDH, menores são as prevalências de DM2, e quanto mais alto o IDH, maiores são prevalências de DM2. Ao nível mundial, o IDH explica 8,6% da variança da prevalência de DM2 (P < 0,0001) e este comportamento difere em cada região do mundo. Conclusões. O IDH pode influir na prevalência de DM2, embora a relação dependa de cada país, região e ano analisados.

[Overview of mortality in Mexico through four indicators from 1990 to 2012]. / Panorama de la mortalidad en México a través de cuatro indicadores de 1990 a 2012.

OBJECTIVE: To describe the behavior of mortality in Mexico through four indicators from 1990 to 2012. MATERIAL AND METHODS: The official mortality and population records of Mexico were used. RESULTS: An advance was achieved for children under five years of age, with a decrease in mortality, although there was an increase in the years of potential life lost (YPLL) from 2008 for this age group. For children under one year of age, there was no advance since 2002 in the index of YPLL and in the productive years of life lost (PYLL). Since 2008 there has been an increase in the rates of mortality, YPLL, and PYLL in the group from 10 to 29 years of age. There has been a sustained increase in YPLL in the age group from 40 to 69. CONCLUSIONS: It is relevant to evaluate the health policies in Mexico for the different age groups; even though there have been positive results in some of them, these are not across all the age groups, which could put some sectors of the population at risk, such as children and young people from 10 to 29 years of age.

[Global prevalence of type 2 diabetes mellitus and its relationship with the Human Development IndexPrevalência mundial da diabetes mellitus tipo 2 e sua relação com o índice de desenvolvimento humano]. / Prevalencia mundial de la diabetes mellitus tipo 2 y su relación con el índice de desarrollo humano.

OBJECTIVE: To evaluate the relationship between the prevalence of type 2 diabetes mellitus (DM2) and the Human Development Index (HDI), by region of the world in the period 2010-2015. METHOD: International Diabetes Federation data were used for DM2 prevalence (2010-2015), together with HDI data (United Nations Development Program). Spearman linear correlations between HDI data and DM2 prevalence were analyzed, and linear regressions were done to estimate the relationship between the two. RESULTS: It was observed that lower HDI scores corresponded to lower DM2 prevalence rates, and higher HDI scores to higher DM2 prevalence. At the global level, the HDI explains the 8.6% variance of DM2 prevalence (P < 0.0001) and shows that the situation was different in each region of the world. CONCLUSIONS: While HDI score may be associated with DM2 prevalence, the relationship between them differs from region to region and from country to country, and depends on the particular year analyzed.

OBJETIVO: Avaliar a relação entre a prevalência de diabetes mellitus tipo 2 (DM2) e o índice de desenvolvimento humano (IDH) por região do mundo no período de 2010 a 2015. MÉTODOS: Foram utilizados dados da Federação Internacional de Diabetes para a prevalência da DM2 (2010­2015) e o IDH do Programa das Nações Unidas para o Desenvolvimento. Foram analisadas as correlações lineares de Spearman entre o IDH e a prevalência de DM2 e feitas regressões lineares para estimar a relação entre ambos. RESULTADOS: Observou-se que quanto mais baixo o IDH, menores são as prevalências de DM2, e quanto mais alto o IDH, maiores são prevalências de DM2. Ao nível mundial, o IDH explica 8,6% da variança da prevalência de DM2 (P < 0,0001) e este comportamento difere em cada região do mundo. CONCLUSÕES: O IDH pode influir na prevalência de DM2, embora a relação dependa de cada país, região e ano analisados.

Prevalencia mundial de la diabetes mellitus tipo 2 y su relación con el índice de desarrollo humano / Global prevalence of type 2 diabetes mellitus and its relationship with the Human Development Index / Prevalência mundial da diabetes mellitus tipo 2 e sua relação com o índice de desenvolvimento humano

RESUMEN Objetivo Evaluar la relación entre la prevalencia de diabetes mellitus tipo 2 (DM2) y el índice de desarrollo humano (IDH) por región del mundo en el período 2010-2015. Método Se utilizaron los datos de la Federación Internacional de Diabetes para la prevalencia de DM2 (2010-2015) y el IDH del Programa de las Naciones Unidas para el Desarrollo. Se analizaron correlaciones lineales de Spearman entre el IDH y la prevalencia de DM2 y se hicieron regresiones lineales para estimar la relación entre ambos. Resultados Se observó que a menor IDH menores son las prevalencias de DM2, y a mayor IDH, mayores son las prevalencias de DM2. A nivel mundial, el IDH explica 8,6% de la varianza de la prevalencia de DM2 (P < 0,0001) y que este comportamiento fue diferente en cada región del mundo. Conclusiones El IDH puede influir en la prevalencia de DM2, aunque la relación depende de cada país, región y año analizado.

ABSTRACT Objective To evaluate the relationship between the prevalence of type 2 diabetes mellitus (DM2) and the Human Development Index (HDI), by region of the world in the period 2010-2015. Method International Diabetes Federation data were used for DM2 prevalence (2010-2015), together with HDI data (United Nations Development Program). Spearman linear correlations between HDI data and DM2 prevalence were analyzed, and linear regressions were done to estimate the relationship between the two. Results It was observed that lower HDI scores corresponded to lower DM2 prevalence rates, and higher HDI scores to higher DM2 prevalence. At the global level, the HDI explains the 8.6% variance of DM2 prevalence (P < 0.0001) and shows that the situation was different in each region of the world. Conclusions While HDI score may be associated with DM2 prevalence, the relationship between them differs from region to region and from country to country, and depends on the particular year analyzed.

RESUMO Objetivo Avaliar a relação entre a prevalência de diabetes mellitus tipo 2 (DM2) e o índice de desenvolvimento humano (IDH) por região do mundo no período de 2010 a 2015. Métodos Foram utilizados dados da Federação Internacional de Diabetes para a prevalência da DM2 (2010-2015) e o IDH do Programa das Nações Unidas para o Desenvolvimento. Foram analisadas as correlações lineares de Spearman entre o IDH e a prevalência de DM2 e feitas regressões lineares para estimar a relação entre ambos. Resultados Observou-se que quanto mais baixo o IDH, menores são as prevalências de DM2, e quanto mais alto o IDH, maiores são prevalências de DM2. Ao nível mundial, o IDH explica 8,6% da variança da prevalência de DM2 (P < 0,0001) e este comportamento difere em cada região do mundo. Conclusões O IDH pode influir na prevalência de DM2, embora a relação dependa de cada país, região e ano analisados.

[Prevalence of unsafe conditions associated to non-intentional needlestick injuries among trainee physicians]. / Prevalencia, condiciones y actos inseguros asociados a punciones accidentales de médicos en formación.

INTRODUCTION: Physicians in training face high-risk clinical situations for needlestick injuries during their training. OBJECTIVE: To determine the prevalence and establish behaviors associated with needlestick injuries. MATERIAL AND METHODS: A cross-sectional study was conducted during the 2012-2013 school year among undergraduate and graduate medical students of a Faculty of Medicine in Mexico. RESULTS: There were a total of 441 questionnaires completed, of which 56.7% of students reported having experienced at least one lesion, of which only 44.5% reported it. The conditions and unsafe acts associated were: female students had a greater risk for the first puncture, whereas male students correlated with three or more punctures; third year students, night shift rounds, the feeling of being rushed by someone else, and the presence of fatigue were risk factors for the first puncture (p < 0.05). CONCLUSIONS: The high prevalence and the underreporting of non-intentional punctures places students at a higher risk of transmissible diseases. Strategies focused on prevention, monitoring, and control of accidental punctures should be implemented by hospitals, schools, and medical schools.